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chrna2 cre r26 tom cells  (Oxford Instruments)
99
Oxford Instruments chrna2 cre r26 tom cells
(A) Confocal image (20 μm, coronal slice) of primary auditory cortex of a <t>Chrna2-Cre/R26</t> tom mouse showing tdTomato+ somas (red) in L5 with dense axonal arborizations in layer 1 (arrow in corner, scale bar = 100 μm). (B) Confocal image and tracing of a biocytin-filled tdTomato+ neuron (green). Reconstruction of soma and dendrites (black) and axon (red; scale bar = 20 μm) shows long axonal projections to layer 1. (C) Confocal images of a biocytin-filled (green) tdTomato+ neuron among several tdTomato+ neurons (red) show that cells have an ovoid cell body in L5, bipolar dendritic morphology, and proximal axonal arborizations. (D) Image illustrating how the Chrna2-Cre/R26 tom axons emerge from the main dendrite (circle). Scale bars = 50 μm. (E) Image showing the long axonal arborizations (arrows) from one biocytin-filled Chrna2-Cre/R26 tom cell (yellow) to layer 1 and the dense axonal ramifications (asterisk) in layer 1 from all Chrna2-Cre/R26 tom cells expressing tdTomato (red). Scale bars = 50 μm. (F) Example from another biocytin-filled Chrna2-Cre/R26 tom cell to emphasize axonal arborization extending laterally in layer 1, seen as a thin yellow axon at the border of the axonal plexus of Chrna2-Cre/R26 tom cell in layer 1. (G) Top : Example current clamp traces from a tdTomato+ cell showing low-threshold, accommodating firing (20 pA response in red, 100 pA in black, 500 ms) and rebound APs (−20 to −80 pA, 500 ms) typical for Martinotti cells. Bottom : Current clamp trace in response to a 200-pA, 1,000-ms-long stimulus used for analysis in (H). (H) Left : The frequency/current (f/I) curve of MCs α2 shows an average firing rate around 20 Hz (at 200 pA, 1,000 ms) indicating slow spiking properties. Middle : Difference in maximum frequency and steady-state frequency for each neuron to a 200 pA, 1,000-ms-long current step highlights an accommodating discharge. The black line depicts the mean adaptation. Right : Spike-frequency adaptation is shown as a function of time. Data ( n = 36 cells) are presented as mean ± standard error of the mean (SEM) and shown in .
Chrna2 Cre R26 Tom Cells, supplied by Oxford Instruments, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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chrna2 cre r26 tom cells - by Bioz Stars, 2026-05
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signal processing toolbox within matlab  (MathWorks Inc)
98
MathWorks Inc signal processing toolbox within matlab
(A) Confocal image (20 μm, coronal slice) of primary auditory cortex of a <t>Chrna2-Cre/R26</t> tom mouse showing tdTomato+ somas (red) in L5 with dense axonal arborizations in layer 1 (arrow in corner, scale bar = 100 μm). (B) Confocal image and tracing of a biocytin-filled tdTomato+ neuron (green). Reconstruction of soma and dendrites (black) and axon (red; scale bar = 20 μm) shows long axonal projections to layer 1. (C) Confocal images of a biocytin-filled (green) tdTomato+ neuron among several tdTomato+ neurons (red) show that cells have an ovoid cell body in L5, bipolar dendritic morphology, and proximal axonal arborizations. (D) Image illustrating how the Chrna2-Cre/R26 tom axons emerge from the main dendrite (circle). Scale bars = 50 μm. (E) Image showing the long axonal arborizations (arrows) from one biocytin-filled Chrna2-Cre/R26 tom cell (yellow) to layer 1 and the dense axonal ramifications (asterisk) in layer 1 from all Chrna2-Cre/R26 tom cells expressing tdTomato (red). Scale bars = 50 μm. (F) Example from another biocytin-filled Chrna2-Cre/R26 tom cell to emphasize axonal arborization extending laterally in layer 1, seen as a thin yellow axon at the border of the axonal plexus of Chrna2-Cre/R26 tom cell in layer 1. (G) Top : Example current clamp traces from a tdTomato+ cell showing low-threshold, accommodating firing (20 pA response in red, 100 pA in black, 500 ms) and rebound APs (−20 to −80 pA, 500 ms) typical for Martinotti cells. Bottom : Current clamp trace in response to a 200-pA, 1,000-ms-long stimulus used for analysis in (H). (H) Left : The frequency/current (f/I) curve of MCs α2 shows an average firing rate around 20 Hz (at 200 pA, 1,000 ms) indicating slow spiking properties. Middle : Difference in maximum frequency and steady-state frequency for each neuron to a 200 pA, 1,000-ms-long current step highlights an accommodating discharge. The black line depicts the mean adaptation. Right : Spike-frequency adaptation is shown as a function of time. Data ( n = 36 cells) are presented as mean ± standard error of the mean (SEM) and shown in .
Signal Processing Toolbox Within Matlab, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 98 stars, based on 1 article reviews
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version 2012b  (MathWorks Inc)
97
MathWorks Inc version 2012b
(A) Confocal image (20 μm, coronal slice) of primary auditory cortex of a <t>Chrna2-Cre/R26</t> tom mouse showing tdTomato+ somas (red) in L5 with dense axonal arborizations in layer 1 (arrow in corner, scale bar = 100 μm). (B) Confocal image and tracing of a biocytin-filled tdTomato+ neuron (green). Reconstruction of soma and dendrites (black) and axon (red; scale bar = 20 μm) shows long axonal projections to layer 1. (C) Confocal images of a biocytin-filled (green) tdTomato+ neuron among several tdTomato+ neurons (red) show that cells have an ovoid cell body in L5, bipolar dendritic morphology, and proximal axonal arborizations. (D) Image illustrating how the Chrna2-Cre/R26 tom axons emerge from the main dendrite (circle). Scale bars = 50 μm. (E) Image showing the long axonal arborizations (arrows) from one biocytin-filled Chrna2-Cre/R26 tom cell (yellow) to layer 1 and the dense axonal ramifications (asterisk) in layer 1 from all Chrna2-Cre/R26 tom cells expressing tdTomato (red). Scale bars = 50 μm. (F) Example from another biocytin-filled Chrna2-Cre/R26 tom cell to emphasize axonal arborization extending laterally in layer 1, seen as a thin yellow axon at the border of the axonal plexus of Chrna2-Cre/R26 tom cell in layer 1. (G) Top : Example current clamp traces from a tdTomato+ cell showing low-threshold, accommodating firing (20 pA response in red, 100 pA in black, 500 ms) and rebound APs (−20 to −80 pA, 500 ms) typical for Martinotti cells. Bottom : Current clamp trace in response to a 200-pA, 1,000-ms-long stimulus used for analysis in (H). (H) Left : The frequency/current (f/I) curve of MCs α2 shows an average firing rate around 20 Hz (at 200 pA, 1,000 ms) indicating slow spiking properties. Middle : Difference in maximum frequency and steady-state frequency for each neuron to a 200 pA, 1,000-ms-long current step highlights an accommodating discharge. The black line depicts the mean adaptation. Right : Spike-frequency adaptation is shown as a function of time. Data ( n = 36 cells) are presented as mean ± standard error of the mean (SEM) and shown in .
Version 2012b, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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social version 21.0  (SPSS Inc)
90
SPSS Inc social version 21.0
(A) Confocal image (20 μm, coronal slice) of primary auditory cortex of a <t>Chrna2-Cre/R26</t> tom mouse showing tdTomato+ somas (red) in L5 with dense axonal arborizations in layer 1 (arrow in corner, scale bar = 100 μm). (B) Confocal image and tracing of a biocytin-filled tdTomato+ neuron (green). Reconstruction of soma and dendrites (black) and axon (red; scale bar = 20 μm) shows long axonal projections to layer 1. (C) Confocal images of a biocytin-filled (green) tdTomato+ neuron among several tdTomato+ neurons (red) show that cells have an ovoid cell body in L5, bipolar dendritic morphology, and proximal axonal arborizations. (D) Image illustrating how the Chrna2-Cre/R26 tom axons emerge from the main dendrite (circle). Scale bars = 50 μm. (E) Image showing the long axonal arborizations (arrows) from one biocytin-filled Chrna2-Cre/R26 tom cell (yellow) to layer 1 and the dense axonal ramifications (asterisk) in layer 1 from all Chrna2-Cre/R26 tom cells expressing tdTomato (red). Scale bars = 50 μm. (F) Example from another biocytin-filled Chrna2-Cre/R26 tom cell to emphasize axonal arborization extending laterally in layer 1, seen as a thin yellow axon at the border of the axonal plexus of Chrna2-Cre/R26 tom cell in layer 1. (G) Top : Example current clamp traces from a tdTomato+ cell showing low-threshold, accommodating firing (20 pA response in red, 100 pA in black, 500 ms) and rebound APs (−20 to −80 pA, 500 ms) typical for Martinotti cells. Bottom : Current clamp trace in response to a 200-pA, 1,000-ms-long stimulus used for analysis in (H). (H) Left : The frequency/current (f/I) curve of MCs α2 shows an average firing rate around 20 Hz (at 200 pA, 1,000 ms) indicating slow spiking properties. Middle : Difference in maximum frequency and steady-state frequency for each neuron to a 200 pA, 1,000-ms-long current step highlights an accommodating discharge. The black line depicts the mean adaptation. Right : Spike-frequency adaptation is shown as a function of time. Data ( n = 36 cells) are presented as mean ± standard error of the mean (SEM) and shown in .
Social Version 21.0, supplied by SPSS Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/social version 21.0/product/SPSS Inc
Average 90 stars, based on 1 article reviews
social version 21.0 - by Bioz Stars, 2026-05
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matlab toolbox  (MathWorks Inc)
96
MathWorks Inc matlab toolbox
(A) Confocal image (20 μm, coronal slice) of primary auditory cortex of a <t>Chrna2-Cre/R26</t> tom mouse showing tdTomato+ somas (red) in L5 with dense axonal arborizations in layer 1 (arrow in corner, scale bar = 100 μm). (B) Confocal image and tracing of a biocytin-filled tdTomato+ neuron (green). Reconstruction of soma and dendrites (black) and axon (red; scale bar = 20 μm) shows long axonal projections to layer 1. (C) Confocal images of a biocytin-filled (green) tdTomato+ neuron among several tdTomato+ neurons (red) show that cells have an ovoid cell body in L5, bipolar dendritic morphology, and proximal axonal arborizations. (D) Image illustrating how the Chrna2-Cre/R26 tom axons emerge from the main dendrite (circle). Scale bars = 50 μm. (E) Image showing the long axonal arborizations (arrows) from one biocytin-filled Chrna2-Cre/R26 tom cell (yellow) to layer 1 and the dense axonal ramifications (asterisk) in layer 1 from all Chrna2-Cre/R26 tom cells expressing tdTomato (red). Scale bars = 50 μm. (F) Example from another biocytin-filled Chrna2-Cre/R26 tom cell to emphasize axonal arborization extending laterally in layer 1, seen as a thin yellow axon at the border of the axonal plexus of Chrna2-Cre/R26 tom cell in layer 1. (G) Top : Example current clamp traces from a tdTomato+ cell showing low-threshold, accommodating firing (20 pA response in red, 100 pA in black, 500 ms) and rebound APs (−20 to −80 pA, 500 ms) typical for Martinotti cells. Bottom : Current clamp trace in response to a 200-pA, 1,000-ms-long stimulus used for analysis in (H). (H) Left : The frequency/current (f/I) curve of MCs α2 shows an average firing rate around 20 Hz (at 200 pA, 1,000 ms) indicating slow spiking properties. Middle : Difference in maximum frequency and steady-state frequency for each neuron to a 200 pA, 1,000-ms-long current step highlights an accommodating discharge. The black line depicts the mean adaptation. Right : Spike-frequency adaptation is shown as a function of time. Data ( n = 36 cells) are presented as mean ± standard error of the mean (SEM) and shown in .
Matlab Toolbox, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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pls_toolbox version 8.2.1  (The Matworks Company LLC)
90
The Matworks Company LLC pls_toolbox version 8.2.1
(A) Confocal image (20 μm, coronal slice) of primary auditory cortex of a <t>Chrna2-Cre/R26</t> tom mouse showing tdTomato+ somas (red) in L5 with dense axonal arborizations in layer 1 (arrow in corner, scale bar = 100 μm). (B) Confocal image and tracing of a biocytin-filled tdTomato+ neuron (green). Reconstruction of soma and dendrites (black) and axon (red; scale bar = 20 μm) shows long axonal projections to layer 1. (C) Confocal images of a biocytin-filled (green) tdTomato+ neuron among several tdTomato+ neurons (red) show that cells have an ovoid cell body in L5, bipolar dendritic morphology, and proximal axonal arborizations. (D) Image illustrating how the Chrna2-Cre/R26 tom axons emerge from the main dendrite (circle). Scale bars = 50 μm. (E) Image showing the long axonal arborizations (arrows) from one biocytin-filled Chrna2-Cre/R26 tom cell (yellow) to layer 1 and the dense axonal ramifications (asterisk) in layer 1 from all Chrna2-Cre/R26 tom cells expressing tdTomato (red). Scale bars = 50 μm. (F) Example from another biocytin-filled Chrna2-Cre/R26 tom cell to emphasize axonal arborization extending laterally in layer 1, seen as a thin yellow axon at the border of the axonal plexus of Chrna2-Cre/R26 tom cell in layer 1. (G) Top : Example current clamp traces from a tdTomato+ cell showing low-threshold, accommodating firing (20 pA response in red, 100 pA in black, 500 ms) and rebound APs (−20 to −80 pA, 500 ms) typical for Martinotti cells. Bottom : Current clamp trace in response to a 200-pA, 1,000-ms-long stimulus used for analysis in (H). (H) Left : The frequency/current (f/I) curve of MCs α2 shows an average firing rate around 20 Hz (at 200 pA, 1,000 ms) indicating slow spiking properties. Middle : Difference in maximum frequency and steady-state frequency for each neuron to a 200 pA, 1,000-ms-long current step highlights an accommodating discharge. The black line depicts the mean adaptation. Right : Spike-frequency adaptation is shown as a function of time. Data ( n = 36 cells) are presented as mean ± standard error of the mean (SEM) and shown in .
Pls Toolbox Version 8.2.1, supplied by The Matworks Company LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/pls_toolbox version 8.2.1/product/The Matworks Company LLC
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pls_toolbox version 8.2.1 - by Bioz Stars, 2026-05
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r version 3.5.0  (RStudio)
90
RStudio r version 3.5.0
(A) Confocal image (20 μm, coronal slice) of primary auditory cortex of a <t>Chrna2-Cre/R26</t> tom mouse showing tdTomato+ somas (red) in L5 with dense axonal arborizations in layer 1 (arrow in corner, scale bar = 100 μm). (B) Confocal image and tracing of a biocytin-filled tdTomato+ neuron (green). Reconstruction of soma and dendrites (black) and axon (red; scale bar = 20 μm) shows long axonal projections to layer 1. (C) Confocal images of a biocytin-filled (green) tdTomato+ neuron among several tdTomato+ neurons (red) show that cells have an ovoid cell body in L5, bipolar dendritic morphology, and proximal axonal arborizations. (D) Image illustrating how the Chrna2-Cre/R26 tom axons emerge from the main dendrite (circle). Scale bars = 50 μm. (E) Image showing the long axonal arborizations (arrows) from one biocytin-filled Chrna2-Cre/R26 tom cell (yellow) to layer 1 and the dense axonal ramifications (asterisk) in layer 1 from all Chrna2-Cre/R26 tom cells expressing tdTomato (red). Scale bars = 50 μm. (F) Example from another biocytin-filled Chrna2-Cre/R26 tom cell to emphasize axonal arborization extending laterally in layer 1, seen as a thin yellow axon at the border of the axonal plexus of Chrna2-Cre/R26 tom cell in layer 1. (G) Top : Example current clamp traces from a tdTomato+ cell showing low-threshold, accommodating firing (20 pA response in red, 100 pA in black, 500 ms) and rebound APs (−20 to −80 pA, 500 ms) typical for Martinotti cells. Bottom : Current clamp trace in response to a 200-pA, 1,000-ms-long stimulus used for analysis in (H). (H) Left : The frequency/current (f/I) curve of MCs α2 shows an average firing rate around 20 Hz (at 200 pA, 1,000 ms) indicating slow spiking properties. Middle : Difference in maximum frequency and steady-state frequency for each neuron to a 200 pA, 1,000-ms-long current step highlights an accommodating discharge. The black line depicts the mean adaptation. Right : Spike-frequency adaptation is shown as a function of time. Data ( n = 36 cells) are presented as mean ± standard error of the mean (SEM) and shown in .
R Version 3.5.0, supplied by RStudio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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prism version 5.0 windows/mac  (GraphPad Software Inc)
90
GraphPad Software Inc prism version 5.0 windows/mac
(A) Confocal image (20 μm, coronal slice) of primary auditory cortex of a <t>Chrna2-Cre/R26</t> tom mouse showing tdTomato+ somas (red) in L5 with dense axonal arborizations in layer 1 (arrow in corner, scale bar = 100 μm). (B) Confocal image and tracing of a biocytin-filled tdTomato+ neuron (green). Reconstruction of soma and dendrites (black) and axon (red; scale bar = 20 μm) shows long axonal projections to layer 1. (C) Confocal images of a biocytin-filled (green) tdTomato+ neuron among several tdTomato+ neurons (red) show that cells have an ovoid cell body in L5, bipolar dendritic morphology, and proximal axonal arborizations. (D) Image illustrating how the Chrna2-Cre/R26 tom axons emerge from the main dendrite (circle). Scale bars = 50 μm. (E) Image showing the long axonal arborizations (arrows) from one biocytin-filled Chrna2-Cre/R26 tom cell (yellow) to layer 1 and the dense axonal ramifications (asterisk) in layer 1 from all Chrna2-Cre/R26 tom cells expressing tdTomato (red). Scale bars = 50 μm. (F) Example from another biocytin-filled Chrna2-Cre/R26 tom cell to emphasize axonal arborization extending laterally in layer 1, seen as a thin yellow axon at the border of the axonal plexus of Chrna2-Cre/R26 tom cell in layer 1. (G) Top : Example current clamp traces from a tdTomato+ cell showing low-threshold, accommodating firing (20 pA response in red, 100 pA in black, 500 ms) and rebound APs (−20 to −80 pA, 500 ms) typical for Martinotti cells. Bottom : Current clamp trace in response to a 200-pA, 1,000-ms-long stimulus used for analysis in (H). (H) Left : The frequency/current (f/I) curve of MCs α2 shows an average firing rate around 20 Hz (at 200 pA, 1,000 ms) indicating slow spiking properties. Middle : Difference in maximum frequency and steady-state frequency for each neuron to a 200 pA, 1,000-ms-long current step highlights an accommodating discharge. The black line depicts the mean adaptation. Right : Spike-frequency adaptation is shown as a function of time. Data ( n = 36 cells) are presented as mean ± standard error of the mean (SEM) and shown in .
Prism Version 5.0 Windows/Mac, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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optimizer version 5.6  (Gurobi Optimization)
90
Gurobi Optimization optimizer version 5.6
(A) Confocal image (20 μm, coronal slice) of primary auditory cortex of a <t>Chrna2-Cre/R26</t> tom mouse showing tdTomato+ somas (red) in L5 with dense axonal arborizations in layer 1 (arrow in corner, scale bar = 100 μm). (B) Confocal image and tracing of a biocytin-filled tdTomato+ neuron (green). Reconstruction of soma and dendrites (black) and axon (red; scale bar = 20 μm) shows long axonal projections to layer 1. (C) Confocal images of a biocytin-filled (green) tdTomato+ neuron among several tdTomato+ neurons (red) show that cells have an ovoid cell body in L5, bipolar dendritic morphology, and proximal axonal arborizations. (D) Image illustrating how the Chrna2-Cre/R26 tom axons emerge from the main dendrite (circle). Scale bars = 50 μm. (E) Image showing the long axonal arborizations (arrows) from one biocytin-filled Chrna2-Cre/R26 tom cell (yellow) to layer 1 and the dense axonal ramifications (asterisk) in layer 1 from all Chrna2-Cre/R26 tom cells expressing tdTomato (red). Scale bars = 50 μm. (F) Example from another biocytin-filled Chrna2-Cre/R26 tom cell to emphasize axonal arborization extending laterally in layer 1, seen as a thin yellow axon at the border of the axonal plexus of Chrna2-Cre/R26 tom cell in layer 1. (G) Top : Example current clamp traces from a tdTomato+ cell showing low-threshold, accommodating firing (20 pA response in red, 100 pA in black, 500 ms) and rebound APs (−20 to −80 pA, 500 ms) typical for Martinotti cells. Bottom : Current clamp trace in response to a 200-pA, 1,000-ms-long stimulus used for analysis in (H). (H) Left : The frequency/current (f/I) curve of MCs α2 shows an average firing rate around 20 Hz (at 200 pA, 1,000 ms) indicating slow spiking properties. Middle : Difference in maximum frequency and steady-state frequency for each neuron to a 200 pA, 1,000-ms-long current step highlights an accommodating discharge. The black line depicts the mean adaptation. Right : Spike-frequency adaptation is shown as a function of time. Data ( n = 36 cells) are presented as mean ± standard error of the mean (SEM) and shown in .
Optimizer Version 5.6, supplied by Gurobi Optimization, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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constant-current power supplies bop 50–4 m  (Kepco Inc)
90
Kepco Inc constant-current power supplies bop 50–4 m
(A) Confocal image (20 μm, coronal slice) of primary auditory cortex of a <t>Chrna2-Cre/R26</t> tom mouse showing tdTomato+ somas (red) in L5 with dense axonal arborizations in layer 1 (arrow in corner, scale bar = 100 μm). (B) Confocal image and tracing of a biocytin-filled tdTomato+ neuron (green). Reconstruction of soma and dendrites (black) and axon (red; scale bar = 20 μm) shows long axonal projections to layer 1. (C) Confocal images of a biocytin-filled (green) tdTomato+ neuron among several tdTomato+ neurons (red) show that cells have an ovoid cell body in L5, bipolar dendritic morphology, and proximal axonal arborizations. (D) Image illustrating how the Chrna2-Cre/R26 tom axons emerge from the main dendrite (circle). Scale bars = 50 μm. (E) Image showing the long axonal arborizations (arrows) from one biocytin-filled Chrna2-Cre/R26 tom cell (yellow) to layer 1 and the dense axonal ramifications (asterisk) in layer 1 from all Chrna2-Cre/R26 tom cells expressing tdTomato (red). Scale bars = 50 μm. (F) Example from another biocytin-filled Chrna2-Cre/R26 tom cell to emphasize axonal arborization extending laterally in layer 1, seen as a thin yellow axon at the border of the axonal plexus of Chrna2-Cre/R26 tom cell in layer 1. (G) Top : Example current clamp traces from a tdTomato+ cell showing low-threshold, accommodating firing (20 pA response in red, 100 pA in black, 500 ms) and rebound APs (−20 to −80 pA, 500 ms) typical for Martinotti cells. Bottom : Current clamp trace in response to a 200-pA, 1,000-ms-long stimulus used for analysis in (H). (H) Left : The frequency/current (f/I) curve of MCs α2 shows an average firing rate around 20 Hz (at 200 pA, 1,000 ms) indicating slow spiking properties. Middle : Difference in maximum frequency and steady-state frequency for each neuron to a 200 pA, 1,000-ms-long current step highlights an accommodating discharge. The black line depicts the mean adaptation. Right : Spike-frequency adaptation is shown as a function of time. Data ( n = 36 cells) are presented as mean ± standard error of the mean (SEM) and shown in .
Constant Current Power Supplies Bop 50–4 M, supplied by Kepco Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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constant-current power supplies bop 50–4 m - by Bioz Stars, 2026-05
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hd215 headphones  (Sennheiser Electronic GmbH Co KG)
90
Sennheiser Electronic GmbH Co KG hd215 headphones
(A) Confocal image (20 μm, coronal slice) of primary auditory cortex of a <t>Chrna2-Cre/R26</t> tom mouse showing tdTomato+ somas (red) in L5 with dense axonal arborizations in layer 1 (arrow in corner, scale bar = 100 μm). (B) Confocal image and tracing of a biocytin-filled tdTomato+ neuron (green). Reconstruction of soma and dendrites (black) and axon (red; scale bar = 20 μm) shows long axonal projections to layer 1. (C) Confocal images of a biocytin-filled (green) tdTomato+ neuron among several tdTomato+ neurons (red) show that cells have an ovoid cell body in L5, bipolar dendritic morphology, and proximal axonal arborizations. (D) Image illustrating how the Chrna2-Cre/R26 tom axons emerge from the main dendrite (circle). Scale bars = 50 μm. (E) Image showing the long axonal arborizations (arrows) from one biocytin-filled Chrna2-Cre/R26 tom cell (yellow) to layer 1 and the dense axonal ramifications (asterisk) in layer 1 from all Chrna2-Cre/R26 tom cells expressing tdTomato (red). Scale bars = 50 μm. (F) Example from another biocytin-filled Chrna2-Cre/R26 tom cell to emphasize axonal arborization extending laterally in layer 1, seen as a thin yellow axon at the border of the axonal plexus of Chrna2-Cre/R26 tom cell in layer 1. (G) Top : Example current clamp traces from a tdTomato+ cell showing low-threshold, accommodating firing (20 pA response in red, 100 pA in black, 500 ms) and rebound APs (−20 to −80 pA, 500 ms) typical for Martinotti cells. Bottom : Current clamp trace in response to a 200-pA, 1,000-ms-long stimulus used for analysis in (H). (H) Left : The frequency/current (f/I) curve of MCs α2 shows an average firing rate around 20 Hz (at 200 pA, 1,000 ms) indicating slow spiking properties. Middle : Difference in maximum frequency and steady-state frequency for each neuron to a 200 pA, 1,000-ms-long current step highlights an accommodating discharge. The black line depicts the mean adaptation. Right : Spike-frequency adaptation is shown as a function of time. Data ( n = 36 cells) are presented as mean ± standard error of the mean (SEM) and shown in .
Hd215 Headphones, supplied by Sennheiser Electronic GmbH Co KG, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
hd215 headphones - by Bioz Stars, 2026-05
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pls-toolbox 7.9  (Eigenvector Research Inc)
90
Eigenvector Research Inc pls-toolbox 7.9
(A) Confocal image (20 μm, coronal slice) of primary auditory cortex of a <t>Chrna2-Cre/R26</t> tom mouse showing tdTomato+ somas (red) in L5 with dense axonal arborizations in layer 1 (arrow in corner, scale bar = 100 μm). (B) Confocal image and tracing of a biocytin-filled tdTomato+ neuron (green). Reconstruction of soma and dendrites (black) and axon (red; scale bar = 20 μm) shows long axonal projections to layer 1. (C) Confocal images of a biocytin-filled (green) tdTomato+ neuron among several tdTomato+ neurons (red) show that cells have an ovoid cell body in L5, bipolar dendritic morphology, and proximal axonal arborizations. (D) Image illustrating how the Chrna2-Cre/R26 tom axons emerge from the main dendrite (circle). Scale bars = 50 μm. (E) Image showing the long axonal arborizations (arrows) from one biocytin-filled Chrna2-Cre/R26 tom cell (yellow) to layer 1 and the dense axonal ramifications (asterisk) in layer 1 from all Chrna2-Cre/R26 tom cells expressing tdTomato (red). Scale bars = 50 μm. (F) Example from another biocytin-filled Chrna2-Cre/R26 tom cell to emphasize axonal arborization extending laterally in layer 1, seen as a thin yellow axon at the border of the axonal plexus of Chrna2-Cre/R26 tom cell in layer 1. (G) Top : Example current clamp traces from a tdTomato+ cell showing low-threshold, accommodating firing (20 pA response in red, 100 pA in black, 500 ms) and rebound APs (−20 to −80 pA, 500 ms) typical for Martinotti cells. Bottom : Current clamp trace in response to a 200-pA, 1,000-ms-long stimulus used for analysis in (H). (H) Left : The frequency/current (f/I) curve of MCs α2 shows an average firing rate around 20 Hz (at 200 pA, 1,000 ms) indicating slow spiking properties. Middle : Difference in maximum frequency and steady-state frequency for each neuron to a 200 pA, 1,000-ms-long current step highlights an accommodating discharge. The black line depicts the mean adaptation. Right : Spike-frequency adaptation is shown as a function of time. Data ( n = 36 cells) are presented as mean ± standard error of the mean (SEM) and shown in .
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(A) Confocal image (20 μm, coronal slice) of primary auditory cortex of a Chrna2-Cre/R26 tom mouse showing tdTomato+ somas (red) in L5 with dense axonal arborizations in layer 1 (arrow in corner, scale bar = 100 μm). (B) Confocal image and tracing of a biocytin-filled tdTomato+ neuron (green). Reconstruction of soma and dendrites (black) and axon (red; scale bar = 20 μm) shows long axonal projections to layer 1. (C) Confocal images of a biocytin-filled (green) tdTomato+ neuron among several tdTomato+ neurons (red) show that cells have an ovoid cell body in L5, bipolar dendritic morphology, and proximal axonal arborizations. (D) Image illustrating how the Chrna2-Cre/R26 tom axons emerge from the main dendrite (circle). Scale bars = 50 μm. (E) Image showing the long axonal arborizations (arrows) from one biocytin-filled Chrna2-Cre/R26 tom cell (yellow) to layer 1 and the dense axonal ramifications (asterisk) in layer 1 from all Chrna2-Cre/R26 tom cells expressing tdTomato (red). Scale bars = 50 μm. (F) Example from another biocytin-filled Chrna2-Cre/R26 tom cell to emphasize axonal arborization extending laterally in layer 1, seen as a thin yellow axon at the border of the axonal plexus of Chrna2-Cre/R26 tom cell in layer 1. (G) Top : Example current clamp traces from a tdTomato+ cell showing low-threshold, accommodating firing (20 pA response in red, 100 pA in black, 500 ms) and rebound APs (−20 to −80 pA, 500 ms) typical for Martinotti cells. Bottom : Current clamp trace in response to a 200-pA, 1,000-ms-long stimulus used for analysis in (H). (H) Left : The frequency/current (f/I) curve of MCs α2 shows an average firing rate around 20 Hz (at 200 pA, 1,000 ms) indicating slow spiking properties. Middle : Difference in maximum frequency and steady-state frequency for each neuron to a 200 pA, 1,000-ms-long current step highlights an accommodating discharge. The black line depicts the mean adaptation. Right : Spike-frequency adaptation is shown as a function of time. Data ( n = 36 cells) are presented as mean ± standard error of the mean (SEM) and shown in .

Journal: PLoS Biology

Article Title: Chrna2-Martinotti Cells Synchronize Layer 5 Type A Pyramidal Cells via Rebound Excitation

doi: 10.1371/journal.pbio.2001392

Figure Lengend Snippet: (A) Confocal image (20 μm, coronal slice) of primary auditory cortex of a Chrna2-Cre/R26 tom mouse showing tdTomato+ somas (red) in L5 with dense axonal arborizations in layer 1 (arrow in corner, scale bar = 100 μm). (B) Confocal image and tracing of a biocytin-filled tdTomato+ neuron (green). Reconstruction of soma and dendrites (black) and axon (red; scale bar = 20 μm) shows long axonal projections to layer 1. (C) Confocal images of a biocytin-filled (green) tdTomato+ neuron among several tdTomato+ neurons (red) show that cells have an ovoid cell body in L5, bipolar dendritic morphology, and proximal axonal arborizations. (D) Image illustrating how the Chrna2-Cre/R26 tom axons emerge from the main dendrite (circle). Scale bars = 50 μm. (E) Image showing the long axonal arborizations (arrows) from one biocytin-filled Chrna2-Cre/R26 tom cell (yellow) to layer 1 and the dense axonal ramifications (asterisk) in layer 1 from all Chrna2-Cre/R26 tom cells expressing tdTomato (red). Scale bars = 50 μm. (F) Example from another biocytin-filled Chrna2-Cre/R26 tom cell to emphasize axonal arborization extending laterally in layer 1, seen as a thin yellow axon at the border of the axonal plexus of Chrna2-Cre/R26 tom cell in layer 1. (G) Top : Example current clamp traces from a tdTomato+ cell showing low-threshold, accommodating firing (20 pA response in red, 100 pA in black, 500 ms) and rebound APs (−20 to −80 pA, 500 ms) typical for Martinotti cells. Bottom : Current clamp trace in response to a 200-pA, 1,000-ms-long stimulus used for analysis in (H). (H) Left : The frequency/current (f/I) curve of MCs α2 shows an average firing rate around 20 Hz (at 200 pA, 1,000 ms) indicating slow spiking properties. Middle : Difference in maximum frequency and steady-state frequency for each neuron to a 200 pA, 1,000-ms-long current step highlights an accommodating discharge. The black line depicts the mean adaptation. Right : Spike-frequency adaptation is shown as a function of time. Data ( n = 36 cells) are presented as mean ± standard error of the mean (SEM) and shown in .

Article Snippet: Chrna2-Cre/ R26 tom cells were counted using Imaris 8.1 (Bitplane) and Matlab (version 2013a, MathWorks) in an 800-μM section (AP: −2.40 to −3.20 mm, ML: 2.00 to 5.00 mm, and DV: 0.50 to 3.50 mm).

Techniques: Expressing